Monday, November 18, 2013

Skin & Soft Tissue Lesions

Skin & Soft Tissue Lesions



Question 1 - Which of the following is NOT a type of melanoma?
Superficial
Nodular
Acral lentiginous
Morpheaform
Question 2 - What is the primary treatment of melanoma?
Excision
Radiation
Conservative treatment
Liquid nitrogen
Question 3 - Which melanoma is the least common in Caucasians, but makes up the bulk of melanoma in African American, Asians and Hispanics?
Superficial spreading melanoma
Nodular
Acral lentiginous
Lentigo maligna melanoma
Amelanotic melanoma
Question 4 - Which of the following is NOT a concern of a melanoma skin lesion?
Asymmetric shape
Borders which are clearly defined
Colour change
Diameter > 6mm
Question 5 - A skin lesion which is ulcerated with rolled, smooth, pearly borders is most likely:
Melanoma
Basal cell carcinoma
Seborrheic keratosis
Squamous cell carcinoma
Question 6 - Which of the following is NOT a pre-malignant (or does not have malignant potential) skin condition/ lesion?
Actinic keratosis
Nevus sebaceous
Dysplastic nevus
Seborrheic keratosis
Question 7 - Which of the following skin lesions is NOT associated with sun exposure?
Actinic keratosis
Basal cell carcinoma
Seborrheic keratosis
Melanoma
Question 8 - Which of the following is TRUE about melanoma?
The most common skin cancer
The most common benign skin cancer
The most common cause of death from skin cancer
The most common skin cancer among Asians
Question 9 - A 65-year-old male presents to clinic with a small skin lesion (0.5 cm) on his chest which is very suspicious for melanoma. Which of the following is the most appropriate option for this patient?
Conservative treatment
Excisional biopsy with wide margins
Immediate chemotherapy and radiotherapy
Immediate CT scan
None of the above
Question 10 - What is the most common basal cell carcinoma?
Sclerosing
Morpheform
Nodular
Pigmented
Superficial
Question 11 - You have excised an irregular pigmented lesion from chest of a 50-year-old woman. The pathology report states that the lesion is melanoma, Clark’s level III. This means that the lesion:
Has invaded into the reticular dermis
Has invaded into the subcutaneous fat
Has not crossed the basement membrane
Has invaded into the papillary-reticular junction
Has invaded into papillary dermis
Question 12 - A man has a suspected melanoma excised from his back. It appears to be less than 1 mm deep. The smallest margin to plan for excision is:
5 cm
2 cm
1 cm
6 cm
2 mm
Question 13 - This subtype of melanoma is the most aggressive, arising in apparently normal skin or in a nevus, and rapidly becoming a firm, elevated nodule of dense black or brown-black colour. The nodule may have bluish hues, and in 5% of cases may be amelanotic (flesh coloured). This subtype, which comprises 15% of all melanoma cases, can arise at any site in the body. The name of this subtype is:
Superficial spreading melanoma
Nodular melanoma
Lentigo maligna melanoma
Acral lentiginous melanoma
Question 14 - This type of skin lesion is elevated, brown, and has a “stuck on” appearance:
Actinic keratosis
Basal cell carcinoma
Xanthoma
Seborrheic keratosis
Verruca
Question 15 - The following are all types of basal cell carcinoma EXCEPT:
Nodular
Pigmented
Marjolin’s ulcer
Morpheaform
Question 16 - What is the most common tumour of the hand?
Basal cell carcinoma
Giant cell
Osteoma
Ganglion cyst
Question 17 - A 40-year-old woman arrives at her family doctor’s office with concern about a black, bleeding lesion on her left lower leg. She states that it has become enlarged over the past several months and more irregular in appearance. Which of the following is FALSE about melanoma?
Excision is the primary management
Nodular melanoma is the most common
Ulceration is a negative prognostic factor
Family history is a risk factor
The most common site on males is the back
Question 18 - The following are true of the skin lesions EXCEPT:
Actinic keratosis is completely benign with no malignant potential
Nodular ulcerative variant is a type of basal cell carcinoma
Squamous cell carcinoma occurs in primarily sun exposed area of skin
Basal cell carcinoma has a 95% cure rate if lesion is less than 2 cm in diameter
Question 19 - Which of the following is NOT associated with Marjolin’s ulcer?
Basal cell carcinoma
Attenuated burn
Squamous cell carcinoma
Inflammation
Aged scar
Question 20 - Risk factors for developing melanoma include all of the following EXCEPT:
Fair skin
Freckles
African American
Actinic keratosis
Question 21 - A tumour descending into the reticular dermis, but not invading the subcutaneous tissue, would be classified as:
Clarks level I
Clarks level III
Clarks level V
Clarks level IV
Question 22 - Which of the following regarding melanoma is TRUE?
Acral lentiginous is the most common subtype
Breslow’s depth of invasion is a more reliable indicator of prognosis than Clark’s levels.
A Breslow depth of <0.76 mm carries a metastases rate of 25%
Complete excisional biopsy is usually not necessary
Question 23 - The best treatment for the removal of actinic keratoses is:
Surgical excision
Topical chemotherapy
Radiation
Cryotherapy with liquid nitrogen
All treatments are equal efficacy
Question 24 - Which nevus would you most likely remove due to its increased malignant potential?
Compound
Intradermal
Junctional
Large pigmented
None of the above
Question 25 - Actinic keratoses are skin lesions that may degenerate into the following skin malignancy:
Lentigo maligna
Basal cell carcinoma
Malignant melanoma
Squamous cell carcinoma
26 Keratoacanthoma is-
a)A type of basal cell carcinoma
b)Infected sebaceous cyst
c)Self healing nodular lesion with central ulceration
d)Pre-malignant disease
27 True about keratoacanthoma –  
a)Benign tumor
b)Malignant skin tumor like squamous cell carcinoma
c)Treatment same as for squamous cell carcinoma
d)Easy to differentiate from squamous cell Ca. histologically
e)Treatment is masterly inactivity
28 Which of the following is a regressing
tumour-  
a) Portwine stain b) Strawberry angioma
c) Venous angioma d) Plexiform angioma
29 Spontaneous regression is seen in all except –
a)Salmon patch
b)Small Cavernous hemangioma 
c)Portwine stain d)Strawberry angioma
30 Least likely to regress spontaneously is
a) Osteosarcoma b) Retinoblasoma
c) Choriocarcinoma d) Malignant melanoma
31 Spontaneous Regresssion is seen in all except –
a) Retinoblasoma b) Malignant melanoma 
c) Osteosarcoma d) Choriocarcinoma
32Cystic hygroma –
a)Should be left alone
b)Excision of cyst at an early age
c)Spontaneous regression
d)Manifests in 2nd – 3rd decade
33 Salmon patch usually disappears by age- a) One mouth b) One year UPSC 89)
c) Puberty d) None of the above
34 Regarding hemangiomas following are true –
a)Salmon patch disappears after the age of one
b)Port wine stain present throughout life
c)Salmon patch-on forehead midline and over occiput
d)all are correct
35 Eleven month old child presents with erythematous lesion with central clearing which has been decreasing in size 
a)Strawberry angioma
b)Nevus
c)Portwine stain
d)Cavernous haemangioma
36 The best cosmetic results for large capillary (port wine) hemangiomas are achieved by
a)Excision and split-thickness skin
b)Laser ablation
c)Cryosurgery
d)Tattooing
37 True about Hemangioma of head & neck   a) Are very common b) Sturge Weber synd
c) High output failure
 d) Thrombocytopenia
38 Hemangioma of the rectum –
a)Common tumour 
b)Fatal haemorrhage seen
c)Ulcerative colitis like symptoms seen
39 True about lymphangioma –  
a)It is a malignant tumour 
b)It is a congenital sequestration of lymphatic
c)Cystic hygroma is a lymphangioma

d)Laser excision is done
e)Sclerotherapy is commonly done’
40 Earliest tumour to appear after bith is-
a) Sternomastoid tumour 
b) Cystic hygroma c) Branchial cyst d) Lymphoma
41 Cystic compressible, translucent swelling in the posterior triangle of neck-  a) Cystic hygroma
c) Thyroglossal cyst
b) Branchial cyst
d) Dermoid cyst
42 Treatment of cystic hygroma is –
a)Surgical excision
b)Injection of sclerosants
c)Irradiation
d)Masterly inactivity
43 The brilliantly transilluminant tumour in the neck may be- (AI 91)
a) Branchial cyst b) Thyroglossal cyst
c) Sternomastoid tumour d) Cystic hygroma
44 All are true about cystic hygroma except –
a)Pulsatile (AMU 95)
b)May cause respiratory obstruction
c)Common in neck
d)Present at birth
45 All are true about cystic hygroma except   a)Aspiration is diagnostic b)50% present at birth
c)Presents as posterior cervical swelling
d)Sequstration of lymphatic tissue
46 True about cystic hygroma –
a)Congenital sequestration of lymphatics
b)Resolves spontaneouly by 5 year of age
c)Common in upper 1/3rd of lateral neck
d)Surgery is the treatment of choice
47 Calcifying epithelioma is also known as —
a)Pilomatrixoma  
b)Myoblastoma
c)Calcinosis cutis
d)Dermatofibroma lenticulare
48 True about Marjolins ulcer –   a)Develops in long standing scar
b)Sq cell Ca develops
c)Slow growing lesion 
d)Also know as Baghdad sore
e)Common in Black races
49 True about marjolins ulcer is – 
a) Ulcer over scar b) Rapid growth
c) Rodent ulcer d) Painful
50 Chronically lymphoedematous limb is predisposed to all of the following except
a)Thickening of the skin
b)Recurrent soft tissue infections 
c)Marjolin’s ulcer d)Sarcoma
51 Chronic lymphedema predisposes to all except  
a) Lymphangiosarcoma b) Marjolins ulcer
c) Recurrent infections d) Thickening of skin
52 Not a premalignant ulcer
a)Bazin’s ulcer
b)Pagets disease of nipple
c)Marjolins ulcer
d)Lupur vulgaris
53 Commonest cancer in burn scar is
a) Sq. cell Ca b) Fibrosarcoma
c) Adenoa Ca d) Adeno-squamous Ca
54 In pigmented basal cell carcinoma, treatment of choice is – 
a) Chemotherapy b) Radiotherapy
c) Cryosurgery d) Excision
55 Diagnostic procedure for basal cell Ca –
a) Wedge biopsy b) Shave
c) Incisional biopsy d) Punch bio
56 Moh’s Micrographic excision for basal cell carcinoma is used for all of the following except –
a)Recurrent Tumour
b)Tumor less than 2 cm in diameter
c)Tumors with aggressive histology
d)Tumors with perineural invasion
57 Basal cell carcinoma spread by –
a) Lymphatics b) Haematogenous
c) Direct spread d) None of the above
58 The commonest clinical pattern of basal cell carcinoma is –  
a) Nodular b) Morpheaform
c) Superficial d) Keratotic
59 A 48-year-old sports photographer has noticed a small nodule over the upper lip from four months. The nodule is pearly white with central necrosis, telangiectasia. The most likely diagnosis would be –
a)Basal cell carcinoma 
b)Squamous cell carcinoma
c)Atypical melanoma
d)Kaposis sarcoma
60 All are true statement about malignant melanoma except-
a)Clark’s classification used for prognosis
b)Women have better prognosis
c)Acral lentigenous have better prognosis
d)Limb perfusion is used for local treatment
61 Prognosis of malignant melanoma depends on –  )
a) Grade of tumor b) Spread of tumor
c) Depth of invasion d) Metastasis
62 Worst prognosis in Melanoma is seen in the subtype-
a)Superficial spreading
b)Nodular Melanoma
c)Lentigo Maligna Melanoma
d)Amelanotic Melanoma
63 Least malignant melanoma is-  
a) Lentigo maligna b) Superifcial spreading
c) Nodular d) Amelanotic
64 Prognosis of melanoma depends on –  
a
)Stage
b)Depth of melanoma on biopsy

c)Duration of growth
d)site
e)brselow thickness 
65 Which one of the following is not included in the treatment of malignant melanoma –
a) Radiation b) Surgical excision
c) Chemotherapy d) Immunotherapy
66 In the Clatke’s level of tumor invasion for malignant melanoma level 3 refers to –
a)All tumar cells above basement membrane
b)Invasion into reticular dermis
c)Invasion into loose connective tissue of papillary dermis
d)Tumor cells at junction of papillary and reticular dermis
67 True about melanoma of the anal canal is - 
a)Present usually as anal bleeding
b)AP resection gives better result than local excision
c)Local recurrence at the same site after resection
d)Radiosensitive
68 Most common site of Ientigo maligna melanoma is -a) Face b) Legs
c) Trunks d) Soles
69 Most common origin of melanoma is from –
a)Junctional melanocytes 
b)Epidermal cells c)Basal cells
d)Follicular cells

3 comments:

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  3. can u provide answers for the upper questions please ?

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